Nutraferon AZANEM Injection

SKU: NF0004 Categories: ,
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Consume Type
Parenteral
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Product Discription

Nutraferon AZANEM Injection – Targeted Parenteral Monobactam Antibiotic for Severe Aerobic Gram-Negative Infections

₹849.00

Nutraferon AZANEM Injection – Overview

Nutraferon AZANEM Injection in critical care and hospital medicine, rapidly controlling severe Gram-negative bacterial infections while preserving renal function and managing beta-lactam allergies is vital. Nutraferon AZANEM Injection is formulated with 1000 mg (1 g) of sterile Aztreonam, a synthetic bactericidal monobactam (monocyclic beta-lactam) antibiotic. Trusted by intensivists, nephrologists, and infectious disease specialists, it provides targeted activity exclusively against susceptible aerobic Gram-negative bacteria.

Unlike broad-spectrum beta-lactams that disrupt protective Gram-positive and anaerobic gastrointestinal flora, Aztreonam selectively targets aerobic Gram-negative bacilli—including Escherichia coli, Klebsiella, Proteus, Enterobacter, and Pseudomonas aeruginosa—and exhibits intrinsic structural resistance to hydrolysis by Ambler Class B metallo-beta-lactamases (MBLs).

Nutraferon AZANEM Injection should be administered only under qualified medical supervision.

Explore our other Nutraferon healthcare products to learn more about our product range. You can also visit our healthcare website for additional information.

Clinical Highlights

  • Selective PBP3 Binding (Monobactam Mechanism): Aztreonam binds with high affinity to penicillin-binding protein 3 (PBP3) of aerobic Gram-negative bacteria, inhibiting septal peptidoglycan synthesis during cell division and causing bacterial filamentation and lysis. It has virtually zero affinity for Gram-positive or anaerobic PBPs.
  • Stability Against Metallo-Beta-Lactamases (MBLs): Because of its monocyclic nucleus, Aztreonam is not hydrolyzed by Class B metallo-beta-lactamases (such as NDM, VIM, and IMP), though it can be inactivated by Class A ESBLs, KPCs, and AmpC enzymes.
  • Renal Excretion Profile: Approximately 60–70% of an administered dose is excreted unchanged in the urine via glomerular filtration and active tubular secretion, requiring dose reduction when creatinine clearance falls below 30 mL/min.

Key Benefits

  • Strict Aerobic Gram-Negative Specificity: Eradicates susceptible Gram-negative rods without disturbing normal Gram-positive or anaerobic mucosal flora.
  • Clears Complicated Urinary Tract Infections (cUTIs) & Pyelonephritis: Achieves high urinary concentrations to resolve severe renal and urinary tract infections.
  • Resolves Lower Respiratory & Bloodstream Infections: Effective for nosocomial pneumonia, bronchitis, and Gram-negative bacteremia/septicemia.
  • Treats Intra-Abdominal, Gynecological, Skin & Bone Infections: Penetrates peritoneal fluid, pelvic tissues, skin, and bone matrices .
  • Valuable Option in Penicillin-Allergic & Nephrology Patients: Offers a non-nephrotoxic alternative to aminoglycosides with minimal cross-allergenicity in patients with IgE-mediated penicillin allergy (except patients allergic to Ceftazidime, which shares an identical side chain).

Directions of Use & Safety Information

  • Professional Clinical Administration Only: For Intravenous (IV) injection/infusion or deep Intramuscular (IM) injection by qualified medical or nursing personnel in a hospital or clinical setting. Do not self-administer.
  • Dosing & Route Selection: Typical adult doses range from 500 mg to 2 g every 6, 8, or 12 hours depending on infection severity. For systemic infections with Pseudomonas aeruginosa, lung infections, or meningitis, the Intravenous (IV) route (up to 2 g every 6–8 hours) is required rather than IM administration.
  • Renal Dose Adjustment: In patients with moderate-to-severe renal impairment (CrCl < 30 mL/min) or on hemodialysis, after a normal initial loading dose, the maintenance dose is reduced by 50% to 75% according to nephrology protocol.

FAQs

Disclaimer

Prescription Only Medicine (Hospital Use Only). Contraindicated in patients with known hypersensitivity to aztreonam. Store dry vials below 25°C protected from light.

Reviews

Description

Nutraferon AZANEM Injection – Overview

Nutraferon AZANEM Injection in critical care and hospital medicine, rapidly controlling severe Gram-negative bacterial infections while preserving renal function and managing beta-lactam allergies is vital. Nutraferon AZANEM Injection is formulated with 1000 mg (1 g) of sterile Aztreonam, a synthetic bactericidal monobactam (monocyclic beta-lactam) antibiotic. Trusted by intensivists, nephrologists, and infectious disease specialists, it provides targeted activity exclusively against susceptible aerobic Gram-negative bacteria.

Unlike broad-spectrum beta-lactams that disrupt protective Gram-positive and anaerobic gastrointestinal flora, Aztreonam selectively targets aerobic Gram-negative bacilli—including Escherichia coli, Klebsiella, Proteus, Enterobacter, and Pseudomonas aeruginosa—and exhibits intrinsic structural resistance to hydrolysis by Ambler Class B metallo-beta-lactamases (MBLs).

Nutraferon AZANEM Injection should be administered only under qualified medical supervision.

Explore our other Nutraferon healthcare products to learn more about our product range. You can also visit our healthcare website for additional information.

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Atchuta Rao Kavuri
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good product
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Satish R
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Excellent quality full range of products at reasonable price.
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Srujan Raga
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Good products and Good customer care and perfect and in time delivery for every clients . Pan India delivery 🚚 and Amazon and Tata 1 Mg products are available 💊 💉 #Nutraferon Pvt LTD#Hyderabad #Telangana #India
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MAHERUNNISA BEGUM
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Good
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Roronoa Zoro
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Nice product with good ingredients.
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Vijay Chowdary
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Good working
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joynikhil
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