Nutraferon NUTRACEF Tablets

Manufacturer/Marketer
Consume Type
Oral
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Product Discription

Nutraferon NUTRACEF Tablets – Third-Generation Cephalosporin / β-Lactamase Inhibitor for Resistant Infections

₹480.00

Nutraferon NUTRACEF Tablets – Overview

Nutraferon NUTRACEF Tablet (325 mg) is a broad-spectrum oral bactericidal formulation combining the third-generation ester-prodrug cephalosporin Cefpodoxime Proxetil (equivalent to 200 mg Cefpodoxime) with the irreversible β-lactamase inhibitor Potassium Clavulanate (equivalent to 125 mg Clavulanic Acid). Engineered for outpatient respiratory, ENT, urinary, and skin infections—as well as oral step-down therapy following parenteral third-generation cephalosporins (`47-Nutraferon NUTRACEF INJ`)—it restores Cefpodoxime’s bactericidal potency against Class A β-lactamase-producing pathogens.

Explore our other Nutraferon healthcare products to learn more about our product range. You can also visit our healthcare website for additional information.

Clinical Highlights

  • Ester Prodrug De-Esterification & PBP3 Inhibition (Cefpodoxime Proxetil 200 mg): The lipophilic proxetil ester facilitates intestinal mucosal uptake, where non-specific esterases hydrolyze it into active Cefpodoxime. Active Cefpodoxime binds bacterial PBP3 to block peptidoglycan transpeptidation and induce osmotic cell lysis.
  • Suicide β-Lactamase Inhibition (Clavulanic Acid 125 mg): Covalently acylates the active serine site of Class A β-lactamases.
  • pH- & Food-Dependent Oral Bioavailability: Cefpodoxime Proxetil requires an acidic gastric environment and food for optimal dissolution—taking it with food increases systemic bioavailability from ~50% to ~70%.

Key Benefits

  • Overcomes Ambler Class A β-Lactamase Resistance: Clavulanic acid irreversibly neutralizes plasmid-mediated Class A β-lactamases (including many ESBLs), safeguarding Cefpodoxime against enzymatic hydrolysis. 
  • Ideal IV-to-Oral Step-Down Bridge: Allows hospitalized patients stabilized on IV Ceftriaxone (`Nutraferon NUTRACEF INJ`) or Cefoperazone to transition smoothly to oral outpatient therapy.
  • Broad Respiratory, ENT & Urinary Coverage: Active against Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis.
  • Convenient Twice-Daily (q12h) Dosing: Extended ~2 to 3 hour plasma half-life maintains tissue concentrations above the minimum inhibitory concentration (MIC) over a 12-hour interval.

Directions of Use & Safety Information

  • Dosage: Take strictly as prescribed by your physician—typically one tablet every 12 hours (twice daily) for 5 to 14 days depending on infection site and severity.
  • Administration & Mandatory Food Timing (Pharmacist Correction): Swallow the tablet whole with a full glass of water WITH food (during a meal). Do not chew, crush, or split the tablet. 
  • Critical Acid-Suppressing Drug Interaction (Antacids, H2 Blockers & PPIs): Do NOT take concurrently with Antacids (aluminum/magnesium hydroxide), H2-receptor blockers (famotidine, ranitidine), or Proton Pump Inhibitors (pantoprazole, rabeprazole, omeprazole), as raising stomach pH significantly reduces the dissolution and absorption of Cefpodoxime Proxetil (cut by 30–40%)! Space antacids by at least 2 hours after taking Nutraferon NUTRACEF TAB.

FAQs

Disclaimer

Prescription Only Medicine (Schedule H1 Antibacterial). Contraindicated in patients with documented hypersensitivity to cephalosporins, penicillins, beta-lactams, or clavulanate-associated cholestatic jaundice. Store below 25°C in original moisture-protective blister foil. Keep out of reach of children.

Reviews

Description

Nutraferon NUTRACEF Tablets – Overview

Nutraferon NUTRACEF Tablet (325 mg) is a broad-spectrum oral bactericidal formulation combining the third-generation ester-prodrug cephalosporin Cefpodoxime Proxetil (equivalent to 200 mg Cefpodoxime) with the irreversible β-lactamase inhibitor Potassium Clavulanate (equivalent to 125 mg Clavulanic Acid). Engineered for outpatient respiratory, ENT, urinary, and skin infections—as well as oral step-down therapy following parenteral third-generation cephalosporins (`47-Nutraferon NUTRACEF INJ`)—it restores Cefpodoxime’s bactericidal potency against Class A β-lactamase-producing pathogens.

Explore our other Nutraferon healthcare products to learn more about our product range. You can also visit our healthcare website for additional information.

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Our Clients Reviews

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Atchuta Rao Kavuri profile picture
Atchuta Rao Kavuri
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good product
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Satish R profile picture
Satish R
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Excellent quality full range of products at reasonable price.
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Srujan Raga profile picture
Srujan Raga
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Good products and Good customer care and perfect and in time delivery for every clients . Pan India delivery 🚚 and Amazon and Tata 1 Mg products are available 💊 💉 #Nutraferon Pvt LTD#Hyderabad #Telangana #India
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MAHERUNNISA BEGUM profile picture
MAHERUNNISA BEGUM
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Good
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Roronoa Zoro profile picture
Roronoa Zoro
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Nice product with good ingredients.
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Vijay Chowdary profile picture
Vijay Chowdary
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Good working
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joynikhil
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