Nutraferon CALCITRO CAP

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Product Discription

Nutraferon CALCITRO Softgel Capsules – Biologically Active Vitamin D3 for Renal Osteodystrophy, Hypoparathyroidism & Metabolic Bone Health

₹335.00

Nutraferon CALCITRO CAP – Overview

For patients managing chronic kidney disease (CKD), hypoparathyroidism, or metabolic bone disease, conventional over-the-counter Vitamin D supplements (cholecalciferol or ergocalciferol) are often clinically insufficient. Nutraferon CALCITRO Softgel Capsule delivers 0.25 mcg of Calcitriol (1,25-dihydroxycholecalciferol)—the hormonally active form of Vitamin D3. Trusted by nephrologists, endocrinologists, and orthopaedic specialists, it bypasses impaired hepatic and renal hydroxylation steps to directly regulate calcium and phosphate homeostasis and protect skeletal mineralization. In healthy physiology, dietary or cutaneous Vitamin D must undergo 25-hydroxylation in the liver followed by 1-alpha-hydroxylation in the proximal renal tubules. When renal parenchyma is damaged in CKD or parathyroid hormone (PTH) signaling is absent in hypoparathyroidism, active calcitriol synthesis fails—leading to hypocalcemia, secondary hyperparathyroidism, and bone resorption. Nutraferon CALCITRO directly supplies the active hormone to restore mineral equilibrium. Explore our other Nutraferon healthcare products to learn more about our product range. You can also visit our healthcare website for additional information.

Clinical Highlights

  • Vitamin D Receptor (VDR) Genomic Activation: Calcitriol binds with high affinity to intracellular Vitamin D Receptors (VDRs) in intestinal enterocytes, parathyroid cells, bone osteoblasts, and distal renal tubules, forming a heterodimer with the Retinoid X Receptor (RXR) to regulate target gene transcription.
  • Intestinal Calcium & Phosphate Upregulation: Stimulates synthesis of calbindin-D9k and apical calcium channels (TRPV6) in the duodenum and jejunum, driving active transcellular calcium and phosphorus absorption.
  • Parathyroid Hormone (PTH) Gene Suppression: Directly downregulates pre-pro-PTH mRNA transcription in the parathyroid glands while increasing parathyroid sensitivity to serum calcium, curbing parathyroid hyperplasia in CKD-MBD.

Key Benefits

  • Prevents & Manages Renal Osteodystrophy:Directly suppresses elevated parathyroid hormone (PTH) secretion and corrects hypocalcemia in pre-dialysis CKD and maintenance dialysis patients.
  • Bypasses Renal 1-Alpha-Hydroxylase Failure: Provides fully activated 1,25-(OH)2D3 that works immediately without requiring enzymatic conversion by failing kidneys.
  • Treats Hypoparathyroidism & Pseudohypoparathyroidism: Restores serum calcium concentrations when endogenous PTH production or receptor signaling is deficient.
  • Supports Postmenopausal & Metabolic Bone Mineralization: Enhances active intestinal calcium transport and osteoblastic bone remodeling to reduce fracture risk.

Directions of Use & Safety Information

  • Dosage: Take strictly in the individualized dose and schedule prescribed by your nephrologist, endocrinologist, or physician (commonly initiated at 0.25 mcg daily or every other day, titrated according to serum calcium and intact PTH levels).
  • Administration: Swallow the softgel capsule whole with a glass of water, with or without food. Do not chew, puncture, or crush the softgel capsule.
  • Mandatory Laboratory Monitoring: Serum calcium, phosphorus, magnesium, alkaline phosphatase, and intact PTH (as well as 24-hour urinary calcium in non-dialysis patients) must be monitored regularly, especially during dose titration.

FAQs

Disclaimer

Prescription Only Medicine (POM). Contraindicated in patients with hypercalcemia or evidence of Vitamin D toxicity. Store in a cool, dry place below 25°C, tightly closed and protected from light and moisture. Keep out of reach of children.

Reviews

Description

Nutraferon CALCITRO CAP – Overview

For patients managing chronic kidney disease (CKD), hypoparathyroidism, or metabolic bone disease, conventional over-the-counter Vitamin D supplements (cholecalciferol or ergocalciferol) are often clinically insufficient. Nutraferon CALCITRO Softgel Capsule delivers 0.25 mcg of Calcitriol (1,25-dihydroxycholecalciferol)—the hormonally active form of Vitamin D3. Trusted by nephrologists, endocrinologists, and orthopaedic specialists, it bypasses impaired hepatic and renal hydroxylation steps to directly regulate calcium and phosphate homeostasis and protect skeletal mineralization.

In healthy physiology, dietary or cutaneous Vitamin D must undergo 25-hydroxylation in the liver followed by 1-alpha-hydroxylation in the proximal renal tubules. When renal parenchyma is damaged in CKD or parathyroid hormone (PTH) signaling is absent in hypoparathyroidism, active calcitriol synthesis fails—leading to hypocalcemia, secondary hyperparathyroidism, and bone resorption. Nutraferon CALCITRO directly supplies the active hormone to restore mineral equilibrium.

Explore our other Nutraferon healthcare products to learn more about our product range. You can also visit our healthcare website for additional information.

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Atchuta Rao Kavuri
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good product
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Satish R
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Excellent quality full range of products at reasonable price.
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Srujan Raga
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Good products and Good customer care and perfect and in time delivery for every clients . Pan India delivery 🚚 and Amazon and Tata 1 Mg products are available 💊 💉 #Nutraferon Pvt LTD#Hyderabad #Telangana #India
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MAHERUNNISA BEGUM
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Good
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Roronoa Zoro
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Nice product with good ingredients.
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Vijay Chowdary
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Good working
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joynikhil
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