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Nutraferon METHOPLUS Injection
METHOPLUS-TAB3
METHOPLUS-TAB2
METHOPLUS-TAB4

Nutraferon METHOPLUS Injection

SKU: NF00039 Categories: , , , , , , , ,
Manufacturer/Marketer
NUTRAFERON PVT LTD
Consume Type
Oral
Return Policy
NOT RETURNABLE

Product Discription

Nutraferon METHOPLUS Injection for Nerve Function, Energy Metabolism & Nutritional Deficiencies

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₹480.00

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Nutraferon METHOPLUS Injection – Overview

Nutraferon METHOPLUS Injection is a sterile, high-potency parenteral multivitamin and neurotrophic formulation containing Methylcobalamin (active Vitamin B12), Thiamine (Vitamin B1), Vitamin B6 (Pyridoxine), Nicotinamide (Vitamin B3), and D-Panthenol (Provitamin B5). Engineered for multi-specialty clinical use across neurology, endocrinology, orthopaedics and rheumatology, nephrology, gastroenterology, gynaecology and infertility, and general medicine, these five water-soluble coenzymes work synergistically to support normal peripheral and central nerve function, cellular energy metabolism, neurotransmitter synthesis, and red blood cell maturation. In clinical practice, Nutraferon METHOPLUS Injection is prescribed to provide rapid parenteral nutritional replenishment in patients with acute or severe B-vitamin deficiencies, heightened metabolic requirements, or impaired gastrointestinal absorption—where oral supplementation (`39-Nutraferon METHOPLUS TAB`) is unfeasible, too slow, or blocked by malabsorption syndromes. Explore our other Nutraferon healthcare products to learn more about our product range. You can also visit our healthcare website for additional information.

Clinical Highlights

  • Direct Transmethylation & Myelin Synthesis (Methylcobalamin / Active Vitamin B12): Unlike synthetic cyanocobalamin, Methylcobalamin requires no hepatic bioconversion. It acts directly as the methyl-donor coenzyme for methionine synthase, remethylating neurotoxic homocysteine into methionine (precursor to S-adenosylmethionine) to drive synthesis of phosphatidylcholine (lecithin) and myelin basic protein in peripheral nerves.
  • Aerobic Glucose Oxidation & Pentose Phosphate Shunt (Thiamine / Vitamin B1): Phosphorylated intracellularly to Thiamine Pyrophosphate (TPP), the essential prosthetic group for pyruvate dehydrogenase, alpha-ketoglutarate dehydrogenase, and transketolase—preventing endoneurial lactic acid accumulation and oxidative nerve injury.
  • Neurotransmitter & Heme Biosynthesis (Vitamin B6 / Pyridoxine): Converted to Pyridoxal-5′-Phosphate (PLP), an indispensable coenzyme for amino acid decarboxylation and transamination required to synthesize GABA, serotonin, dopamine, norepinephrine, myelin sphingolipids, and heme (δ-aminolevulinic acid synthase).
  • NAD+/NADP+ Redox & Coenzyme A Synthesis (Nicotinamide [B3] & D-Panthenol [B5]): Nicotinamide serves as the direct precursor to NAD+ and NADP+ for mitochondrial electron transport chain ATP production, while D-Panthenol converts into Pantothenic Acid (Vitamin B5)—the structural core of Coenzyme A (CoA) required for acetylcholine synthesis and lipid metabolism.

Key Benefits

  • Immediate 100% Parenteral Bioavailability: Bypasses gastrointestinal absorption barriers (such as pernicious anaemia, intrinsic factor deficiency, atrophic gastritis, bariatric surgery, IBD, or severe diabetic gastroparesis) to deliver active neurotrophic vitamins directly into the bloodstream.
  • Restores Peripheral Nerve Conduction & Myelin Integrity: Methylcobalamin and Pyridoxine (Vitamin B6) accelerate myelin sheath phospholipid repair and axonal regeneration, relieving neuropathic tingling, numbness, burning, and radicular nerve pain.
  • Optimizes Cellular & Neuronal ATP Energy Metabolism: Thiamine (B1), Nicotinamide (B3), and D-Panthenol (B5) act as obligatory mitochondrial coenzymes in glycolysis, the Krebs cycle, and fatty acid oxidation to combat metabolic fatigue and neuronal exhaustion.
  • Replenishes Dialysis- & Illness-Depleted Vitamin Reserves: Rapidly corrects water-soluble B-vitamin depletion in maintenance haemodialysis patients (nephrology), chronic vomiting or hyperemesis (gastroenterology and obstetrics), and convalescent catabolic states.
  • Supports Homocysteine Clearance & Reproductive Metabolism: Methylcobalamin and Vitamin B6 lower elevated plasma homocysteine, supporting endothelial microcirculation, endocrine balance, and preconception/gynaecological health.

Directions of Use & Safety Information

  • Strictly Professional Clinical Administration Only: Your physician, clinician, or registered nurse will administer this medicine via deep Intramuscular (IM) injection or slow Intravenous (IV) injection/infusion according to your clinical deficiency status. Kindly do not self-administer.
  • Critical Pharmacy Handling & Administration Precautions (Highlighted Safety Alert):
    • Protect from Light (Photolabile Active Ingredients): Methylcobalamin and Pyridoxine are highly sensitive to photodegradation; keep ampoules sealed inside their light-protective carton until immediately before drawing up the dose.
    • Slow Intravenous Administration Rate: When administered intravenously (undiluted slow push or diluted in 0.9% Sodium Chloride drip), always inject or infuse slowly (over at least 3 to 5 minutes for bolus or 15 to 30 minutes for infusion), as rapid IV push of parenteral Thiamine (Vitamin B1) can rarely trigger venous irritation, flushing, or anaphylactoid hypersensitivity reactions.
    • IV Line Incompatibilities: Never mix Nutraferon METHOPLUS Injection in the same syringe or infusion bag with alkaline solutions (such as Sodium Bicarbonate), carbonates, barbiturates, or sulfite-containing solutions, as alkaline pH and sulfites rapidly degrade Thiamine and B-complex vitamins.

FAQs

Disclaimer

Prescription Only Medicine (POM — Clinical / Hospital IM or IV Use Only). Contraindicated in patients with known hypersensitivity to cobalamins (Vitamin B12), cobalt, thiamine, or any excipient, and in patients with hereditary Leber’s optic atrophy (where cobalamin administration can accelerate optic nerve atrophy). Store below 25°C in original light-protective packaging; do not freeze. Keep out of reach of children.

Reviews

Description

Nutraferon METHOPLUS Injection – Overview

Nutraferon METHOPLUS Injection is a sterile, high-potency parenteral multivitamin and neurotrophic formulation containing Methylcobalamin (active Vitamin B12), Thiamine (Vitamin B1), Vitamin B6 (Pyridoxine), Nicotinamide (Vitamin B3), and D-Panthenol (Provitamin B5). Engineered for multi-specialty clinical use across neurology, endocrinology, orthopaedics and rheumatology, nephrology, gastroenterology, gynaecology and infertility, and general medicine, these five water-soluble coenzymes work synergistically to support normal peripheral and central nerve function, cellular energy metabolism, neurotransmitter synthesis, and red blood cell maturation.

In clinical practice, Nutraferon METHOPLUS Injection is prescribed to provide rapid parenteral nutritional replenishment in patients with acute or severe B-vitamin deficiencies, heightened metabolic requirements, or impaired gastrointestinal absorption—where oral supplementation (`39-Nutraferon METHOPLUS TAB`) is unfeasible, too slow, or blocked by malabsorption syndromes.

Explore our other Nutraferon healthcare products to learn more about our product range. You can also visit our healthcare website for additional information.

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 Atchuta Rao Kavuri profile picture 
 
 
 Atchuta Rao Kavuri 
 
 
 
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good product
  
 
 
  
 
 
 
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 Satish R 
 
 
 
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Excellent quality full range of products at reasonable price.
  
 
 
  
 
 
 
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 Srujan Raga 
 
 
 
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Good products and Good customer care and perfect and in time delivery for every clients .
Pan India delivery 🚚 and Amazon and Tata 1 Mg products are available   💊 💉
#Nutraferon Pvt LTD#Hyderabad #Telangana #India
  
 
 
  
 
 
 
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 MAHERUNNISA BEGUM 
 
 
 
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Good
  
 
 
  
 
 
 
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 Roronoa Zoro 
 
 
 
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Nice product with good ingredients.
  
 
 
  
 
 
 
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 Vijay Chowdary 
 
 
 
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Good working
  
 
 
  
 
 
 
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 joynikhil 
 
 
 
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Good

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