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Nutraferon MOXINDIA Injection
MOXINDIA-INJ3
MOXINDIA-INJ4
MOXINDIA-INJ2

Nutraferon MOXINDIA Injection

SKU: NF00042 Categories: , ,
Manufacturer/Marketer
NUTRAFERON PVT LTD
Consume Type
Parenteral
Return Policy
NOT RETURNABLE

Product Discription

Nutraferon MOXINDIA Injection – Intravenous β-Lactam/β-Lactamase Inhibitor for Severe Acute Infections

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₹480.00

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Nutraferon MOXINDIA Injection – Overview

Nutraferon MOXINDIA 1.2 g Injection is a sterile, hospital-grade parenteral bactericidal combination pairing the semi-synthetic aminopenicillin Amoxicillin Sodium (equivalent to 1000 mg Amoxicillin) with the irreversible β-lactamase inhibitor Potassium Clavulanate (equivalent to 200 mg Clavulanic Acid) in a 5:1 ratio. Engineered for inpatient hospital wards, intensive care units, emergency medicine, and perioperative surgical prophylaxis, it delivers immediate 100% intravenous bioavailability against β-lactamase-producing Gram-positive, Gram-negative, and anaerobic pathogens when oral therapy is unfeasible or rapid systemic tissue saturation is required. Many common hospital and community bacteria produce β-lactamase enzymes that hydrolyze and inactivate standard penicillins before they can eradicate the infection. In Nutraferon MOXINDIA 1.2 g Injection, Potassium Clavulanate acts as a protective suicide inhibitor that permanently neutralizes Ambler Class A β-lactamase enzymes, restoring and expanding Amoxicillin’s bactericidal spectrum across respiratory, urinary, intra-abdominal, pelvic, bone, and skin/soft-tissue infections. Explore our other Nutraferon healthcare products to learn more about our product range. You can also visit our healthcare website for additional information.

Clinical Highlights

  • Bactericidal PBP Transpeptidation Blockade (Amoxicillin Sodium 1000 mg): Binds selectively to bacterial penicillin-binding proteins (PBP1, PBP2, and PBP3), halting the final transpeptidation step of peptidoglycan synthesis and triggering autolytic cell-wall rupture.
  • Irreversible Class A β-Lactamase Suicide Inhibition (Potassium Clavulanate 200 mg): Features a clavam ring that covalently acylates the active serine site of Ambler Class A β-lactamases (including plasmid-mediated TEM, SHV, and staphylococcal penicillinases), preventing hydrolysis of Amoxicillin’s β-lactam ring.
  • Parenteral Pharmacokinetics: Following a 1.2 g intravenous bolus or infusion, peak plasma concentrations are achieved immediately with a ~1-hour elimination half-life, low plasma protein binding (~18% for amoxicillin; ~25% for clavulanate), and predominant renal clearance (60–70% of amoxicillin and 40–65% of clavulanate excreted unchanged in urine within 6 hours).

Key Benefits

  • Immediate 100% Intravenous Bioavailability: Bypasses gastrointestinal absorption to achieve rapid bactericidal serum and tissue concentrations in acute inpatient infections and nil-by-mouth (NPO) surgical patients.
  • Overcomes Ambler Class A β-Lactamase Resistance: Potassium Clavulanate (200 mg) irreversibly neutralizes staphylococcal penicillinases and Class A extended-spectrum β-lactamases (ESBLs), protecting Amoxicillin (1000 mg) from enzymatic breakdown.
  • Broad Inpatient & Perioperative Coverage: Clinically indicated for severe lower respiratory tract infections, complicated urinary tract infections (cUTI) and pyelonephritis, intra-abdominal and pelvic sepsis, severe skin, soft-tissue, and bone/joint infections, and surgical prophylaxis.
  • Seamless IV-to-Oral Step-Down Bridge: Enables smooth inpatient transition from intravenous `Nutraferon MOXINDIA INJ (1.2 g)` to oral `Nutraferon MOXINDIA TAB (625 mg)` once the patient is afebrile and tolerating oral intake.

Directions of Use & Safety Information

  • Strictly Intravenous (IV) Hospital Administration Only: Your physician, clinician, or registered nurse will administer this medicine exclusively via the Intravenous (IV) route—either as a slow IV injection over 3 to 4 minutes or as an intermittent IV infusion over 30 to 40 minutes. Kindly do not self-administer. Never administer Intramuscularly (IM) due to solution concentration limits and local pain.
  • Reconstitution, Diluent & Stability Protocol:
  • Reconstitution: Dissolve the 1.2 g vial in 20 mL of Sterile Water for Injection (final volume ~20.9 mL). For IV infusion, dilute the reconstituted solution immediately in 100 mL of 0.9% Sodium Chloride (Normal Saline) or Water for Injection.
  • Strict Diluent Incompatibilities: Never reconstitute or dilute in Dextrose (Glucose), Dextran, or Sodium Bicarbonate solutions, as Amoxicillin-Clavulanate undergoes rapid chemical degradation in carbohydrate and alkaline fluids. Never mix in the same syringe or IV line with Aminoglycosides (causes chemical inactivation of the aminoglycoside) or blood products.
  • Administration Time Window: Reconstituted IV bolus solutions must be administered within 20 minutes of preparation, and diluted 0.9% Normal Saline infusions must be completed within 60 minutes.
  • Standard Adult Dosing & Renal Adjustment: Typically 1.2 g IV every 8 hours (or every 6 hours in severe infections). In patients with moderate-to-severe renal impairment (CrCl < 30 mL/min), after an initial 1.2 g loading dose, the maintenance dose and dosing interval must be adjusted by the nephrologist or physician (with a supplemental dose after haemodialysis).

FAQs

Disclaimer

Prescription Only Medicine (POM — Hospital Intravenous Use Only). Strictly contraindicated in patients with a history of severe hypersensitivity (such as anaphylaxis or severe cutaneous adverse reactions) to any penicillin or β-lactam antibacterial agent, or a previous history of amoxicillin-clavulanate-associated cholestatic jaundice or hepatic dysfunction. Store dry unopened vials below 25°C in original packaging protected from moisture and light. Keep out of reach of children.

Reviews

Description

Nutraferon MOXINDIA Injection – Overview

Nutraferon MOXINDIA 1.2 g Injection is a sterile, hospital-grade parenteral bactericidal combination pairing the semi-synthetic aminopenicillin Amoxicillin Sodium (equivalent to 1000 mg Amoxicillin) with the irreversible β-lactamase inhibitor Potassium Clavulanate (equivalent to 200 mg Clavulanic Acid) in a 5:1 ratio. Engineered for inpatient hospital wards, intensive care units, emergency medicine, and perioperative surgical prophylaxis, it delivers immediate 100% intravenous bioavailability against β-lactamase-producing Gram-positive, Gram-negative, and anaerobic pathogens when oral therapy is unfeasible or rapid systemic tissue saturation is required.

Many common hospital and community bacteria produce β-lactamase enzymes that hydrolyze and inactivate standard penicillins before they can eradicate the infection. In Nutraferon MOXINDIA 1.2 g Injection, Potassium Clavulanate acts as a protective suicide inhibitor that permanently neutralizes Ambler Class A β-lactamase enzymes, restoring and expanding Amoxicillin’s bactericidal spectrum across respiratory, urinary, intra-abdominal, pelvic, bone, and skin/soft-tissue infections.

Explore our other Nutraferon healthcare products to learn more about our product range. You can also visit our healthcare website for additional information.

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 Atchuta Rao Kavuri 
 
 
 
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good product
  
 
 
  
 
 
 
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 Satish R 
 
 
 
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Excellent quality full range of products at reasonable price.
  
 
 
  
 
 
 
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 Srujan Raga 
 
 
 
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Good products and Good customer care and perfect and in time delivery for every clients .
Pan India delivery 🚚 and Amazon and Tata 1 Mg products are available   💊 💉
#Nutraferon Pvt LTD#Hyderabad #Telangana #India
  
 
 
  
 
 
 
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 MAHERUNNISA BEGUM 
 
 
 
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Nice product with good ingredients.
  
 
 
  
 
 
 
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Good working
  
 
 
  
 
 
 
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