Nutraferon ERTIGA 500MG Injection

SKU: NF00016 Categories: , ,
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Parenteral
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Product Discription

Nutraferon ERTIGA 500 mg Injection for Severe Susceptible Bacterial Infections

₹480.00

Nutraferon ERTIGA 500MG Injection – Overview

Nutraferon ERTIGA 500 mg Injection delivers the once-daily Group 1 carbapenem Ertapenem (500 mg as Ertapenem Sodium) in a dedicated 500 mg vial engineered specifically for patients with advanced renal impairment (CrCl ≤ 30 mL/min or hemodialysis) and pediatric dosing. It provides potent bactericidal coverage against ESBL- and AmpC-producing Enterobacterales, susceptible Gram-positive aerobes, and anaerobes without partial-vial wastage. Explore our other Nutraferon healthcare products to learn more about our product range. You can also visit our healthcare website for additional information.

Clinical Highlights

  • Bactericidal Cell-Wall Inhibition: Binds bacterial penicillin-binding proteins PBP2 and PBP3, halting peptidoglycan cross-linking and triggering osmotic lysis of susceptible aerobic and anaerobic pathogens.
  • High Stability to Renal DHP-I & Extended-Spectrum Beta-Lactamases: The 1-beta-methyl group protects Ertapenem from hydrolysis by human renal dehydropeptidase-I (DHP-I), while its trans-hydroxyethyl side chain confers stability against ESBLs and AmpC beta-lactamases.
  • Pharmacokinetics in Renal Impairment: In patients with severe renal insufficiency (CrCl ≤ 30 mL/min) or ESRD, the AUC of unbound Ertapenem approximately doubles, making the 500 mg once-daily dose pharmacodynamically equivalent to 1000 mg daily in normal renal function.

Key Benefits

  • Dedicated 500 mg Strength for Advanced CKD & Dialysis: Matches the exact 500 mg once-daily maintenance dose recommended for adult patients with severe renal insufficiency (CrCl ≤ 30 mL/min/1.73 m2) and end-stage renal disease (ESRD).
  • Potent Activity Against ESBL-Producing Enterobacterales: Highly effective against ESBL-producing Escherichia coli and Klebsiella pneumoniae in complicated UTIs, intra-abdominal, pelvic, and diabetic foot infections.
  • Once-Daily Administration: Extended ~4-hour half-life (further prolonged in renal impairment) supports once-daily IV or IM dosing.
  • Eliminates Reconstitution Wastage: Prevents dosing calculation errors and drug waste when treating nephrology or pediatric patients.

Directions of Use & Safety Information

  • Professional Clinical Administration Only: Administered via Intravenous (IV) infusion over 30 minutes or deep Intramuscular (IM) injection by qualified healthcare professionals. Do not self-administer.
  • Critical Reconstitution & Diluent Rules (Pharmacist Alert):
    • For IV Infusion: Reconstitute and dilute exclusively in 0.9% Sodium Chloride (Normal Saline). NEVER dilute or mix Ertapenem in Dextrose/Glucose solutions or co-infuse with other medications.
    • For IM Injection: Reconstitute with 0% Lidocaine HCl injection (without epinephrine) for deep gluteal/thigh muscle injection; never administer lidocaine-reconstituted solutions intravenously.
  • Hemodialysis Timing Tip: Ideally administer the 500 mg dose after the hemodialysis session; if administered within 6 hours prior to hemodialysis, a supplemental dose of 150 mg is recommended post-dialysis.

FAQs

Disclaimer

Prescription Only Medicine (Schedule H1 / Hospital Use Only). Contraindicated in patients with known hypersensitivity to carbapenems, anaphylactic beta-lactam reactions, or amide local anesthetics (for IM lidocaine reconstitution). Store dry vials below 25°C.

Reviews

Description

Nutraferon ERTIGA 500MG Injection – Overview

Nutraferon ERTIGA 500 mg Injection delivers the once-daily Group 1 carbapenem Ertapenem (500 mg as Ertapenem Sodium) in a dedicated 500 mg vial engineered specifically for patients with advanced renal impairment (CrCl ≤ 30 mL/min or hemodialysis) and pediatric dosing. It provides potent bactericidal coverage against ESBL- and AmpC-producing Enterobacterales, susceptible Gram-positive aerobes, and anaerobes without partial-vial wastage.

Explore our other Nutraferon healthcare products to learn more about our product range. You can also visit our healthcare website for additional information.

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Atchuta Rao Kavuri
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good product
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Satish R
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Excellent quality full range of products at reasonable price.
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Srujan Raga
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Good products and Good customer care and perfect and in time delivery for every clients . Pan India delivery 🚚 and Amazon and Tata 1 Mg products are available 💊 💉 #Nutraferon Pvt LTD#Hyderabad #Telangana #India
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MAHERUNNISA BEGUM
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Good
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Roronoa Zoro
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Nice product with good ingredients.
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Vijay Chowdary
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Good working
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joynikhil
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