Nutraferon FLIMAT-P Tablets

SKU: NF00021 Categories: ,
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Product Discription

Nutraferon FLIMAT-P Tablets – Dual-Action Non-Opioid Analgesic & Muscle-Tone Normalizer for Acute Musculoskeletal Pain

₹480.00

Nutraferon FLIMAT-P Tablets – Overview

Nutraferon FLIMAT-P Tablet is a fixed-dose combination analgesic pairing Flupirtine Maleate (100 mg), a centrally acting Selective Neuronal Potassium Channel Opener (SNEPCO), with Paracetamol (325 mg), a centrally acting antipyretic analgesic. Formulated for short-term management of acute musculoskeletal pain, muscle spasms, tension headaches, and post-traumatic/post-surgical pain when other analgesics (such as NSAIDs) are contraindicated or unsuitable, it provides multimodal pain relief and skeletal muscle tone normalization without opioid receptor activity.   CRITICAL PHARMACIST & REGULATORY HEPATOTOXICITY ALERT: Both Flupirtine and Paracetamol undergo hepatic metabolism and carry a serious, cumulative risk of severe drug-induced liver injury (DILI) and acute liver failure. Regulatory authorities (including EMA and CDSCO) have issued strict hepatotoxicity warnings and regulatory restrictions on Flupirtine combinations. Therapy must be restricted strictly to short-term acute pain (never exceeding 2 weeks), is strictly contraindicated in any pre-existing liver disease or alcohol use, and requires baseline and weekly liver function test (AST/ALT/bilirubin) monitoring. Explore our other Nutraferon healthcare products to learn more about our product range. You can also visit our healthcare website for additional information.

Clinical Highlights

  • Selective Neuronal Potassium Channel Opening (Flupirtine 100 mg): Activates voltage-independent Kv7 (KCNQ) potassium channels on dorsal horn nociceptive neurons, hyperpolarizing the neuronal resting membrane potential. This indirectly blocks NMDA receptor activation by maintaining the Mg2+ channel block, preventing central pain sensitization (“wind-up”) and normalizing hypertonic motor neuron firing.
  • Central Antinociception (Paracetamol 325 mg): Inhibits central nervous system prostaglandin synthesis (COX-2/peroxidase site) and activates descending serotonergic pain-inhibitory pathways.
  • Hepatic Clearance & Reactive Metabolite Risk: Both drugs are metabolized in the liver; concurrent oxidative/glucuronidation strain increases hepatotoxic vulnerability, requiring strict adherence to maximum daily dose limits.

Key Benefits

  • Multimodal Non-Opioid Analgesia: Combines neuronal potassium channel opening (Flupirtine) with central prostaglandin and cannabinoid/serotonergic pain modulation (Paracetamol).
  • Normalizes Increased Skeletal Muscle Tone: Relaxes painful local muscle spasms around injured joints and vertebrae without causing generalized neuromuscular blockade.
  • Relieves Acute Musculoskeletal & Post-Traumatic Pain: Effective for acute low back spasm, cervical spondylosis flares, tension headaches, and post-operative pain when NSAIDs are contraindicated.
  • Gastric-Sparing Compared to Classical NSAIDs: Does not inhibit peripheral gastric mucosal COX-1 prostaglandins.

Directions of Use & Safety Information

  • Dosage & Strict Duration Limit: Take strictly as prescribed by your physician for the shortest effective duration (strictly not to exceed 2 weeks).
  • Administration: Swallow the tablet whole with water during or immediately after a meal to minimize nausea. Do not chew, crush, or break the tablet.
  • Hepatotoxicity & Overdose Prevention: Never combine with any other Paracetamol-containing cold, flu, or pain medications, and strictly avoid alcohol during treatment.

FAQs

Disclaimer

Prescription Only Medicine. Contraindicated in pre-existing liver disease, cholestasis, alcoholism, myasthenia gravis, pregnancy, and lactation. Store below 25°C protected from moisture and light. Keep out of reach of children.

Reviews

Description

Nutraferon FLIMAT-P Tablets – Overview

Nutraferon FLIMAT-P Tablet is a fixed-dose combination analgesic pairing Flupirtine Maleate (100 mg), a centrally acting Selective Neuronal Potassium Channel Opener (SNEPCO), with Paracetamol (325 mg), a centrally acting antipyretic analgesic. Formulated for short-term management of acute musculoskeletal pain, muscle spasms, tension headaches, and post-traumatic/post-surgical pain when other analgesics (such as NSAIDs) are contraindicated or unsuitable, it provides multimodal pain relief and skeletal muscle tone normalization without opioid receptor activity.

 

CRITICAL PHARMACIST & REGULATORY HEPATOTOXICITY ALERT: Both Flupirtine and Paracetamol undergo hepatic metabolism and carry a serious, cumulative risk of severe drug-induced liver injury (DILI) and acute liver failure. Regulatory authorities (including EMA and CDSCO) have issued strict hepatotoxicity warnings and regulatory restrictions on Flupirtine combinations. Therapy must be restricted strictly to short-term acute pain (never exceeding 2 weeks), is strictly contraindicated in any pre-existing liver disease or alcohol use, and requires baseline and weekly liver function test (AST/ALT/bilirubin) monitoring.

Explore our other Nutraferon healthcare products to learn more about our product range. You can also visit our healthcare website for additional information.

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Our Clients Reviews

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Atchuta Rao Kavuri profile picture
Atchuta Rao Kavuri
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good product
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Satish R profile picture
Satish R
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Excellent quality full range of products at reasonable price.
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Srujan Raga
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Good products and Good customer care and perfect and in time delivery for every clients . Pan India delivery 🚚 and Amazon and Tata 1 Mg products are available 💊 💉 #Nutraferon Pvt LTD#Hyderabad #Telangana #India
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MAHERUNNISA BEGUM
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Good
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Roronoa Zoro
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Nice product with good ingredients.
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Vijay Chowdary
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Good working
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joynikhil
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