Nutraferon METHOPLUS Tablet

PEA is a natural lipid signaling molecule produced by the body in response to nerve injury and inflammation. Supplementing PEA calms overactive mast cells and microglial cells around nerve fibers, reducing neuro-inflammatory firing without opioid or sedative effects.

It targets shared mechanisms of peripheral nerve distress—whether caused by diabetic metabolic stress (endocrinology), spinal nerve root compression/sciatica (orthopaedics), or deep pelvic/pudendal nerve hypersensitivity (gynaecology).

High blood sugar generates free radicals that damage the tiny blood vessels feeding peripheral nerves (vasa nervorum). Alpha-Lipoic Acid neutralizes these free radicals, regenerates glutathione, and improves insulin sensitivity.

It complements standard neuropathic pain medications (such as pregabalin or gabapentin). However, because it contains Soy Isoflavones (Daidzein and Genistein, which have phytoestrogenic activity), patients with current or past estrogen-receptor-positive (ER+) breast or endometrial cancer, or those taking aromatase inhibitors (such as Letrozole / `Nutraferon LETROO TAB`) or Tamoxifen, should consult their oncologist before use.

Initial improvements in tingling, burning, or numbness are typically noticed after 4 to 8 weeks of daily use, with cumulative structural benefits over 3 to 6 months.