Nutraferon METHOPRA-NT Tablets

Neuropathic pain involves multiple simultaneous mechanisms. Pregabalin quiets overactive sensory nerve terminals, Nortriptyline boosts the spinal cord's natural pain-blocking filter, and Methylcobalamin repairs damaged myelin sheaths—achieving superior pain relief at lower, better-tolerated doses of each agent.

Both Pregabalin and Nortriptyline can cause drowsiness and dizziness, especially during the first 1 to 2 weeks. Taking the tablet at bedtime turns this mild sedation into a therapeutic advantage by helping patients sleep through nighttime nerve pain while reducing daytime grogginess.

No. Stopping Pregabalin or Nortriptyline abruptly can trigger rebound pain, headache, insomnia, nausea, anxiety, or seizures. Always follow a gradual tapering schedule set by your doctor.

Pregabalin is excreted >90% unchanged by the kidneys, so impaired renal function (CrCl < 60 mL/min) causes Pregabalin accumulation, excessive sedation, dizziness, and fall risk. Elderly patients are also more sensitive to Nortriptyline's anticholinergic effects (dry mouth, constipation, urinary retention, blurred vision).

Nutraferon METHOPRA-NT is strictly contraindicated within 14 days of Monoamine Oxidase Inhibitors (MAOIs), during the acute recovery phase after a myocardial infarction (heart attack), or in patients with Brugada syndrome / severe cardiac conduction block, untreated narrow-angle glaucoma, or severe urinary retention. Avoid combining with opioids, benzodiazepines, or alcohol, which dangerously increase the risk of life-threatening CNS and respiratory depression.