Nutraferon GRANY Tablets

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Product Discription

Nutraferon GRANY Tablets for Chemotherapy & Radiotherapy-Induced Nausea and Vomiting

₹480.00

Nutraferon GRANY Tablets – Overview

Nutraferon GRANY Tablet is a potent, highly selective serotonin 5-HT3 receptor antagonist formulated with Granisetron Hydrochloride (typically 1 mg or 2 mg per film-coated tablet—strength was omitted in the original file). Engineered for oncology and radiation supportive care, it prevents acute and delayed nausea and vomiting triggered by emetogenic cancer chemotherapy (CINV) and whole-body or abdominal radiotherapy (RINV). Explore our other Nutraferon healthcare products to learn more about our product range. You can also visit our healthcare website for additional information.2

Clinical Highlights

  • Peripheral & Central 5-HT3 Receptor Blockade: Cytotoxic chemotherapy and abdominal radiation damage intestinal enterochromaffin cells, releasing massive amounts of serotonin (5-HT). Granisetron selectively blocks 5-HT3 receptors on peripheral vagal afferent terminals in the gut and centrally in the chemoreceptor trigger zone (CTZ) of the area postrema, interrupting the vomiting reflex arc.
  • CYP3A4-Predominant Hepatic Metabolism (Non-CYP2D6 Dependent): Unlike ondansetron and tropisetron, Granisetron is metabolized primarily via hepatic CYP3A4 and CYP1A1 without reliance on polymorphic CYP2D6, preserving efficacy in CYP2D6 ultra-rapid metabolizers.

Key Benefits

  • High Selectivity & Extended Receptor Affinity: Exhibits high-affinity binding to 5-HT3 receptors with negligible affinity for dopamine, histamine, or muscarinic receptors—preventing extrapyramidal symptoms or heavy sedation.
  • Prolonged Half-Life (~9 Hours in Oncology Patients): Longer elimination half-life than ondansetron (~3–4 hours), enabling convenient once-daily (2 mg) or twice-daily (1 mg) oral prophylaxis.
  • Prevents Chemotherapy-Induced Nausea & Vomiting (CINV): Blocks acute emetic signaling triggered by moderately and highly emetogenic antineoplastic regimens.
  • Protects Against Radiotherapy-Induced Nausea & Vomiting (RINV): Prevents radiation-triggered enterochromaffin serotonin release during total-body or fractionated abdominal irradiation.

Directions of Use & Safety Information

  • Dosage & Timing: Take strictly as prescribed by your oncologist or physician. For chemotherapy or radiotherapy prophylaxis, the first dose (typically 2 mg once daily or 1 mg twice daily) is administered up to 1 hour before the start of chemotherapy or radiation (and the second 1 mg dose, if prescribed, 12 hours later).
    (Pharmacist Clinical Note: For Postoperative Nausea and Vomiting [PONV], intravenous Granisetron—`27-Nutraferon GRANY 3ML INJ`—is the standard clinical route rather than oral tablets.)
  • Administration: Swallow the tablet whole with water, with or without food. Do not chew, crush, or split the tablet.

FAQs

Disclaimer

Prescription Only Medicine (POM). Contraindicated in patients with hypersensitivity to granisetron or other 5-HT3 receptor antagonists, or concomitant apomorphine use. Store below 25°C protected from light and moisture. Keep out of reach of children.

Reviews

Description

Nutraferon GRANY Tablets – Overview

Nutraferon GRANY Tablet is a potent, highly selective serotonin 5-HT3 receptor antagonist formulated with Granisetron Hydrochloride (typically 1 mg or 2 mg per film-coated tablet—strength was omitted in the original file). Engineered for oncology and radiation supportive care, it prevents acute and delayed nausea and vomiting triggered by emetogenic cancer chemotherapy (CINV) and whole-body or abdominal radiotherapy (RINV).

Explore our other Nutraferon healthcare products to learn more about our product range. You can also visit our healthcare website for additional information.2

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Atchuta Rao Kavuri
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good product
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Satish R
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Excellent quality full range of products at reasonable price.
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Srujan Raga
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Good products and Good customer care and perfect and in time delivery for every clients . Pan India delivery 🚚 and Amazon and Tata 1 Mg products are available 💊 💉 #Nutraferon Pvt LTD#Hyderabad #Telangana #India
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MAHERUNNISA BEGUM
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Good
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Roronoa Zoro
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Nice product with good ingredients.
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Vijay Chowdary
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Good working
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joynikhil
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