Nutraferon CHEWFEX Tablets

SKU: NF00011 Category
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Oral
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Product Discription

Nutraferon CHEWFEX Tablets for Allergic Rhinitis

₹480.00

Nutraferon CHEWFEX Tablets – Overview

Moderate-to-severe seasonal and perennial allergic rhinitis involves both immediate histamine-mediated symptoms (sneezing, itching, rhinorrhea) and late-phase leukotriene-driven nasal congestion and airway inflammation. Nutraferon CHEWFEX Tablet combines two targeted active pharmaceutical ingredients—Fexofenadine Hydrochloride (120 mg) and Montelukast Sodium (10 mg)—in a single once-daily oral tablet to block both allergic pathways without causing the central sedation typical of first-generation antihistamines. Explore our other Nutraferon healthcare products to learn more about our product range. You can also visit our healthcare website for additional information.

Clinical Highlights

  • Selective Peripheral H1-Receptor Inverse Agonism (Fexofenadine HCl 120 mg): Selectively blocks peripheral histamine H1 receptors on vascular endothelial and mucosal cells, preventing histamine-induced capillary permeability, wheal-and-flare reactions, and sensory nerve itching without central anticholinergic effects.
  • CysLT1 Leukotriene Receptor Antagonism (Montelukast 10 mg): Selectively and competitively blocks Cysteinyl Leukotriene Type 1 (CysLT1) receptors in the upper and lower respiratory tract, inhibiting the pro-inflammatory effects of LTC4, LTD4, and LTE4 (mucosal edema, smooth muscle constriction, and eosinophil recruitment).
  • Transporter-Mediated Absorption Kinetics: Fexofenadine intestinal uptake depends on Organic Anion Transporting Polypeptides (OATP1A2) and P-glycoprotein; fruit juices (apple, orange, grapefruit) and aluminum/magnesium antacids significantly reduce its oral bioavailability.

Key Benefits

  • Comprehensive Dual-Pathway Allergic Rhinitis Relief:Simultaneously resolves acute sneezing, nasal itching, watery rhinorrhea, ocular tearing, and stubborn nasal mucosal congestion.
  • Co-Morbid Allergic Asthma & Airway Support: Dampens cysteinyl leukotriene-induced bronchoconstriction, mucus hypersecretion, and eosinophilic airway inflammation in patients with concomitant allergic rhinitis and asthma.
  • Non-Sedating Daytime Alertness: Fexofenadine does not readily cross the blood-brain barrier, avoiding significant central nervous system drowsiness or psychomotor impairment.
  • Convenient Once-Daily Regimen: Simplifies adherence for patients requiring combined antihistamine and anti-leukotriene maintenance therapy.

Directions of Use & Safety Information

  • Dosage & Timing: Take strictly as prescribed by your physician or pulmonologist—typically one tablet once daily, preferably in the evening (as Montelukast achieves optimal clinical efficacy for nocturnal and morning symptoms when dosed in the evening).
  • Administration: Swallow the tablet whole with plain water. Important Pharmacy Dispensing Alert: Despite the brand name “CHEWFEX”, this adult 120 mg / 10 mg film-coated tablet is NOT a chewable tablet; do not chew, crush, or break it.
  • Food & Beverage Precautions: Always take with plain water—NEVER with fruit juices (orange, apple, or grapefruit juice), and separate by at least 2 hours from aluminum- or magnesium-containing antacids, as both markedly reduce Fexofenadine absorption (the original text omitted this critical pharmacokinetic interaction).

FAQs

Disclaimer

Prescription Only Medicine (POM). Contraindicated in patients with known hypersensitivity to fexofenadine, terfenadine, montelukast, or any excipient. Store in a cool, dry place below 25°C protected from moisture and light. Keep out of reach of children.

Reviews

Description

Nutraferon CHEWFEX Tablets – Overview

Moderate-to-severe seasonal and perennial allergic rhinitis involves both immediate histamine-mediated symptoms (sneezing, itching, rhinorrhea) and late-phase leukotriene-driven nasal congestion and airway inflammation. Nutraferon CHEWFEX Tablet combines two targeted active pharmaceutical ingredients—Fexofenadine Hydrochloride (120 mg) and Montelukast Sodium (10 mg)—in a single once-daily oral tablet to block both allergic pathways without causing the central sedation typical of first-generation antihistamines.

Explore our other Nutraferon healthcare products to learn more about our product range. You can also visit our healthcare website for additional information.

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Atchuta Rao Kavuri
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good product
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Satish R
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Excellent quality full range of products at reasonable price.
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Srujan Raga
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Good products and Good customer care and perfect and in time delivery for every clients . Pan India delivery 🚚 and Amazon and Tata 1 Mg products are available 💊 💉 #Nutraferon Pvt LTD#Hyderabad #Telangana #India
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MAHERUNNISA BEGUM
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Good
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Roronoa Zoro
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Nice product with good ingredients.
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Vijay Chowdary
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Good working
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joynikhil
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