Nutraferon I-TEN+ Injection

Nutraferon I-TEN+ Injection contains Ferric Carboxymaltose (50 mg/mL), a more tightly bound third-generation iron complex that allows up to 1000 mg of elemental iron to be infused in a single 15-minute session. By comparison, standard 30-Nutraferon I-TEN INJ contains Iron Sucrose (20 mg/mL), which is limited to 100–200 mg per session and requires 5 to 10 separate clinic visits to replace the same total iron deficit.

In CKD (nephrology), inflammatory bowel disease (gastroenterology), and cancer therapy (oncology), chronic inflammation elevates a hormone called hepcidin that blocks oral iron absorption in the gut. In gynaecology and obstetrics, heavy uterine bleeding or late pregnancy often requires rapid hemoglobin restoration that oral iron cannot achieve quickly enough. Intravenous Ferric Carboxymaltose bypasses the gut entirely to restore iron stores rapidly.

Intravenous Ferric Carboxymaltose is contraindicated during the first trimester of pregnancy (first 13 weeks), where oral iron is used if needed. During the second and third trimesters, it is widely prescribed under direct obstetric supervision when rapid correction of moderate-to-severe iron deficiency anaemia is essential for maternal and fetal health. Maternal vital signs and fetal heart rate are monitored closely during infusion.

Important Clinical Pharmacist Pearl: Ferric Carboxymaltose can transiently increase levels of the hormone Fibroblast Growth Factor 23 (FGF23), which causes the kidneys to excrete extra phosphorus in the urine (hypophosphatemia). While often mild and asymptomatic, patients requiring repeat high-dose infusions—or those with pre-existing Vitamin D deficiency, malabsorption, or osteoporosis—should have serum phosphate and Vitamin D levels monitored to prevent symptomatic hypophosphatemia (fatigue, muscle weakness, or bone pain).

No. Oral iron supplements must be stopped prior to receiving Nutraferon I-TEN+ Injection because parenteral iron reduces oral iron absorption and increases gastrointestinal side effects. If oral maintenance iron is needed later, wait at least 5 days after the final injection before starting oral iron.