Nutraferon PSR FORTY Injection

SKU: NF00071 Categories: ,
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Consume Type
Parenteral
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Product Discription

Nutraferon PSR FORTY Injection for Acute Peptic Ulcer Bleeding, Stress Ulcer Prophylaxis, Severe GORD & Zollinger-Ellison Syndrome

₹480.00

Nutraferon PSR FORTY Injection – Overview

Nutraferon PSR FORTY Injection is a sterile, lyophilized parenteral proton pump inhibitor containing Pantoprazole Sodium Sesquihydrate (equivalent to 40 mg of Pantoprazole per vial). Formulated for emergency departments, endoscopy suites, intensive care units, and NPO surgical wards, it bypasses enteral absorption to deliver immediate systemic acid suppression when oral administration is impossible or rapid intragastric pH elevation (>6.0) is required to stabilize bleeding peptic ulcers.

Explore our other Nutraferon healthcare products to learn more about our product range. You can also visit our healthcare website for additional information.

Clinical Highlights

  • Irreversible H+/K+-ATPase Inhibition: Parenteral Pantoprazole circulates to the acidic canaliculi of gastric parietal cells, where it converts into its active sulfenamide form and covalently binds cysteine-813 and cysteine-822 on the alpha subunit of the H+/K+-ATPase enzyme.
  • Haemostatic pH Threshold (pH > 6.0 vs. pH < 4.0): In an acidic gastric lumen (pH < 4.0), platelet aggregation is impaired by >50% and pepsin actively lyses fibrin blood clots. Sustaining intragastric neutralisation (pH > 6.0) completely inactivates pepsin and preserves haemostatic platelet plugs at the ulcer base.

Key Benefits

  • Immediate 100% Intravenous Bioavailability: Elevates intragastric pH within 15 to 60 minutes without relying on gastric emptying or intestinal absorption.
  • Stabilizes Clots in Acute Peptic Ulcer Bleeding: Sustains intragastric pH > 6.0 after endoscopic haemostasis, preventing pepsin-mediated fibrinolysis and platelet disaggregation to reduce rebleeding.
  • ICU Stress Mucosal Ulcer Prophylaxis: Protects mechanically ventilated, coagulopathic, and NPO surgical patients against upper GI haemorrhage.
  • Titratable Control in Zollinger-Ellison Syndrome: Controls extreme pathological acid hypersecretion (80 mg IV every 8–12 hours) when oral therapy is interrupted.

Directions of Use & Safety Information

  • Strictly Intravenous (IV) Hospital Administration Only: Administered exclusively by qualified physicians or nurses. Never administer intramuscularly or subcutaneously.
  • Reconstitution & Administration Protocols:
  • 2-Minute Direct IV Injection: Reconstitute the 40 mg vial with 10 mL of sterile 0.9% Sodium Chloride (yields 4 mg/mL) and inject slowly over at least 2 minutes.
  • 15-Minute IV Infusion: Reconstitute with 10 mL of 0.9% Sodium Chloride, then dilute further in 100 mL of 0.9% Sodium Chloride or 5% Dextrose (yields ~0.4 mg/mL) and infuse over 15 minutes.
  • High-Dose Peptic Ulcer Bleeding Protocol (After Endoscopic Haemostasis): Typically an 80 mg IV bolus (two 40 mg vials) followed by a continuous infusion of 8 mg/hour for 72 hours (or 40 mg IV every 12 hours), then stepped down to oral `70-Nutraferon PSR 40MG TAB`.
  • Critical IV Line Incompatibility & Zinc Precaution: Never mix or co-infuse through the same line with other medications, midazolam, or parenteral nutrition (high alkaline pH 9.0–10.5 causes precipitation); always flush the IV line with 0.9% NaCl or 5% Dextrose before and after. 

Note: Lyophilized Pantoprazole IV formulations containing edetate disodium (EDTA) chelate zinc ions—consider zinc supplementation in patients on prolonged IV therapy or TPN.

FAQs

Disclaimer

Prescription Only Medicine (POM — Hospital IV Use Only). Contraindicated in patients with known hypersensitivity to pantoprazole, substituted benzimidazoles, or concurrent rilpivirine therapy. Store unopened vials below 25°C in original carton to protect from light (reconstituted solution is photosensitive and degrades if exposed to light). Keep out of reach of children.

Reviews

Description

Nutraferon PSR FORTY Injection – Overview

Nutraferon PSR FORTY Injection is a sterile, lyophilized parenteral proton pump inhibitor containing Pantoprazole Sodium Sesquihydrate (equivalent to 40 mg of Pantoprazole per vial). Formulated for emergency departments, endoscopy suites, intensive care units, and NPO surgical wards, it bypasses enteral absorption to deliver immediate systemic acid suppression when oral administration is impossible or rapid intragastric pH elevation (>6.0) is required to stabilize bleeding peptic ulcers.

Explore our other Nutraferon healthcare products to learn more about our product range. You can also visit our healthcare website for additional information.

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Atchuta Rao Kavuri profile picture
Atchuta Rao Kavuri
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good product
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Satish R profile picture
Satish R
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Excellent quality full range of products at reasonable price.
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Srujan Raga
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Good products and Good customer care and perfect and in time delivery for every clients . Pan India delivery 🚚 and Amazon and Tata 1 Mg products are available 💊 💉 #Nutraferon Pvt LTD#Hyderabad #Telangana #India
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MAHERUNNISA BEGUM
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Good
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Roronoa Zoro
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Nice product with good ingredients.
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Vijay Chowdary
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Good working
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joynikhil
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