Nutraferon MYTRANS-S 360 TAB

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Product Discription

Nutraferon MYTRANS-S 360 mg Tablets – for Renal Allograft Prophylaxis & Autoimmune Nephritis

₹480.00

Nutraferon MYTRANS-S 360 TAB – Overview

Nutraferon MYTRANS-S 360 Tablet DR is an enteric-coated, delayed-release antimetabolite immunosuppressant containing 360 mg of Mycophenolate Sodium (stoichiometrically equimolar to 500 mg of mycophenolate mofetil). Prescribed by transplant nephrologists and rheumatologists in combination with calcineurin inhibitors (cyclosporine or tacrolimus) and corticosteroids, it selectively inhibits de novo purine synthesis in T and B lymphocytes to prevent acute renal allograft rejection and manage severe autoimmune disorders such as Lupus Nephritis.

Explore our other Nutraferon healthcare products to learn more about our product range. You can also visit our healthcare website for additional information.

Clinical Highlights

  • Selective, Reversible Type II IMPDH Inhibition: Active mycophenolic acid (MPA) acts as a potent, non-competitive, reversible inhibitor of Inosine Monophosphate Dehydrogenase (IMPDH), preferentially targeting the Type II isoform expressed in activated T and B lymphocytes (5-fold higher affinity than Type I IMPDH in resting cells).
  • Guanosine Nucleotide Depletion & S-Phase Arrest: Depletes intracellular GTP and dGTP pools, arresting lymphocyte DNA replication in the S-phase and inhibiting fucosylation/mannosylation of adhesion molecules (VLA-4, selectin ligands) required for leukocyte infiltration into the graft.
  • Enterohepatic Recirculation Kinetics: MPA is glucuronidated by hepatic UGT enzymes into inactive MPAG, which is excreted into bile and deconjugated by gut flora back into active MPA (producing a secondary plasma peak at 6–12 hours).

Key Benefits

  • Proven Renal Allograft Preservation: Significantly reduces acute cellular and humoral rejection episodes in kidney transplant recipients.
  • Enteric-Coated Upper GI Tolerability: Delayed-release coating prevents drug dissolution in the acidic stomach (releasing active mycophenolic acid at pH ≥ 5.5 in the small intestine), reducing upper gastrointestinal dyspepsia, nausea, and dose-limiting intolerance.
  • Selective T- & B-Lymphocyte Cytostasis: Targets the de novo purine pathway used exclusively by proliferating lymphocytes while sparing non-immune tissues that utilize the HGPRT salvage pathway.
  • Steroid-Sparing Autoimmune Efficacy: Effective induction and maintenance therapy in Class III–V Lupus Nephritis and refractory autoimmune vasculitis.

Directions of Use & Safety Information

  • Dosage: Strictly as prescribed by your transplant nephrologist or rheumatologist—standard adult renal transplant dose is 720 mg (two 360 mg tablets) twice daily (1440 mg/day total) at fixed 12-hour intervals.
  • Administration & Empty-Stomach Timing: Swallow the delayed-release tablet whole with water on an empty stomach (1 hour before or 2 hours after meals). Never crush, chew, or cut the tablet (destroys the enteric coating and exposes handlers to teratogenic powder).
  • Critical Pharmacy Non-Interchangeability Rule: Do NOT interchange or substitute Mycophenolate Sodium 360 mg delayed-release tablets (`Mytrans-S 360`) with Mycophenolate Mofetil (`MMF 500 mg`) without explicit specialist supervision, because their absorption kinetics and peak plasma profiles differ.

FAQs

Disclaimer

Prescription Only Medicine (High-Alert Transplant Immunosuppressant). Boxed warnings apply for embryo-fetal toxicity, serious opportunistic infections (CMV, BK virus, PML), and lymphoma/skin malignancy risk (use sun protection and avoid live attenuated vaccines). Store below 25°C in original blister pack. Keep out of reach of children.

Reviews

Description

Nutraferon MYTRANS-S 360 TAB – Overview

Nutraferon MYTRANS-S 360 Tablet DR is an enteric-coated, delayed-release antimetabolite immunosuppressant containing 360 mg of Mycophenolate Sodium (stoichiometrically equimolar to 500 mg of mycophenolate mofetil). Prescribed by transplant nephrologists and rheumatologists in combination with calcineurin inhibitors (cyclosporine or tacrolimus) and corticosteroids, it selectively inhibits de novo purine synthesis in T and B lymphocytes to prevent acute renal allograft rejection and manage severe autoimmune disorders such as Lupus Nephritis.

Explore our other Nutraferon healthcare products to learn more about our product range. You can also visit our healthcare website for additional information.

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Atchuta Rao Kavuri
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good product
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Satish R
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Excellent quality full range of products at reasonable price.
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Srujan Raga
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Good products and Good customer care and perfect and in time delivery for every clients . Pan India delivery 🚚 and Amazon and Tata 1 Mg products are available 💊 💉 #Nutraferon Pvt LTD#Hyderabad #Telangana #India
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MAHERUNNISA BEGUM
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Good
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Roronoa Zoro
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Nice product with good ingredients.
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Vijay Chowdary
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Good working
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joynikhil
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